Reaction Details Report a problem with these data
Target
Large envelope protein
Ligand
BDBM590006
Substrate
n/a
Meas. Tech.
Assay Measuring Activity of Test Compounds on Viral Production from HepAD38 Cells
EC50
5250±n/a nM
Citation
 Haydar, SN; Li, L; Bures, MG; Rai, R; Bannen, L; Walker, M 5-membered heteroaryl carboxamide compounds for treatment of HBV US Patent  US11560370 Publication Date 1/24/2023 
Target
Name:
Large envelope protein
Synonyms:
HBSAG_HBVD3 | S
Type:
n/a
Mol. Mass.:
42772.52
Organism:
Hepatitis B virus
Description:
P03138
Residue:
389
Sequence:
MGQNLSTSNPLGFFPDHQLDPAFRANTANPDWDFNPNKDTWPDANKVGAGAFGLGFTPPHGGLLGWSPQAQGILQTLPANPPPASTNRQSGRQPTPLSPPLRNTHPQAMQWNSTTFHQTLQDPRVRGLYFPAGGSSSGTVNPVLTTASPLSSIFSRIGDPALNMENITSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGTTVCLGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCRTCMTTAQGTSMYPSCCCTKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWYWGPSLYSILSPFLPLLPIFFCLWVYI
  
Inhibitor
Name:
BDBM590006
Synonyms:
US11560370, Compound AIA-202C
Type:
Small organic molecule
Emp. Form.:
C22H22ClFN4O
Mol. Mass.:
412.888
SMILES:
Cn1nc([C@H]2CC[C@@H](C2)c2ccccc2)c(C(=O)Nc2ccc(F)c(Cl)c2)c1N |r|
Structure:
Search PDB for entries with ligand similarity: