Reaction Details Report a problem with these data
Target
Myosin light chain kinase family member 4
Ligand
BDBM597763
Substrate
n/a
Meas. Tech.
n Vitro Effect Assay
IC50
>1000±n/a nM
Citation
 Fu, C; Liu, C; Chen, Y; Tu, C; Hung, C Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and method for performing an in vivo related application that benefits from the inhibition of a kinase US Patent  US11608319 Publication Date 3/21/2023 
Target
Name:
Myosin light chain kinase family member 4
Synonyms:
MYLK4 | MYLK4_HUMAN | SGK085
Type:
PROTEIN
Mol. Mass.:
44505.40
Organism:
Homo sapiens (Human)
Description:
ChEMBL_774289
Residue:
388
Sequence:
MLKVKRLEEFNTCYNSNQLEKMAFFQCREEVEKVKCFLEKNSGDQDSRSGHNEAKEVWSNADLTERMPVKSKRTSALAVDIPAPPAPFDHRIVTAKQGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLNAQKKKNRGSDAQDFVTK
  
Inhibitor
Name:
BDBM597763
Synonyms:
US11608319, Compound 10
Type:
Small organic molecule
Emp. Form.:
C27H26N4O3
Mol. Mass.:
454.5203
SMILES:
Cc1ccc(C(=O)Oc2ccc(cc2)C(CN)C(=O)Nc2ccc(cc2)-c2cn[nH]c2)c(C)c1
Structure:
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