Reaction Details Report a problem with these data
Target
Apelin
Ligand
BDBM610914
Substrate
n/a
Meas. Tech.
Measurement of Apelin Receptor Agonist Activity
EC50
2870±n/a nM
Citation
 Ikeda, T; Kobayashi, Y; Miyoshi, N; Suzuki, O; Nagayama, T; Tsuji, T; Smith, LH; Pinkerton, AB Azole derivatives as apelin receptor agonist US Patent  US10626096 Publication Date 4/21/2020 
Target
Name:
Apelin
Synonyms:
APEL | APEL_HUMAN | APJ endogenous ligand | APLN | Apelin-13 | Apelin-28 | Apelin-31 | Apelin-36
Type:
PROTEIN
Mol. Mass.:
8579.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108275
Residue:
77
Sequence:
MNLRLCVQALLLLWLSLTAVCGGSLMPLPDGNGLEDGNVRHLVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF
  
Inhibitor
Name:
BDBM610914
Synonyms:
US10626096, Example 27
Type:
Small organic molecule
Emp. Form.:
C17H16N4O4S
Mol. Mass.:
372.398
SMILES:
COc1cccc(OC)c1-n1c(SCC(O)=O)nnc1-c1cccnc1 |(-1.58,-3.76,;-.81,-2.42,;.73,-2.42,;1.5,-3.76,;3.04,-3.76,;3.81,-2.42,;3.04,-1.09,;3.81,.24,;5.35,.24,;1.5,-1.09,;.73,.24,;-.8,.41,;-1.83,-.74,;-3.34,-.42,;-4.37,-1.56,;-5.88,-1.24,;-3.89,-3.03,;-1.12,1.91,;.21,2.68,;1.36,1.65,;2.86,1.97,;3.89,.83,;5.4,1.15,;5.88,2.61,;4.84,3.76,;3.34,3.44,)|
Structure:
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