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Target
DNA gyrase inhibitor
Ligand
BDBM635591
Substrate
n/a
Meas. Tech.
SDFQ HTS Assay
IC50
37500±n/a nM
Citation
 LENG, F; ALFONSO, E; DENG, Z; NEFZI, A; ROHDE, K BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF US Patent  US20230364057 Publication Date 11/16/2023 
Target
Name:
DNA gyrase inhibitor
Synonyms:
SBMC_ECOLI | gyrI | sbmC | yeeB
Type:
Protein
Mol. Mass.:
18071.67
Organism:
n/a
Description:
P33012
Residue:
157
Sequence:
MNYEIKQEEKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVPKEWVAVYYDNPDETPAEKLRCDTVVTVPGYFTLPENSEGVILTEITGGQYAVAVARVVGDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH
 
Inhibitor
Name:
BDBM635591
Synonyms:
US20230364057, Compound 104
Type:
Small organic molecule
Emp. Form.:
C25H20N2O5S
Mol. Mass.:
460.502
SMILES:
CCc1ccc(cc1)S(=O)(=O)\N=C1\C=C(Nc2ccc(cc2)C(O)=O)C(=O)c2ccccc12 |t:14|
Structure:
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