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Target
Transcription factor SOX-18
Ligand
BDBM22971
Substrate
n/a
Meas. Tech.
Inhibition of Sox18-DNA Binding Assay
IC50
163000±17700 nM
Citation
 FRANCOIS, M; ZUEGG, J; OVERMAN, J; MAMIDYALA, SK; SALIM, AA; FONTAINE, FR; COOPER, MA; CAPON, RJ; ROBERTSON, AA COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT US Patent  US20240002326 Publication Date 1/4/2024 
Target
Name:
Transcription factor SOX-18
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
40895.30
Organism:
Human
Description:
P35713
Residue:
384
Sequence:
MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLPGLAPPQPPPEPFPAASGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAPLAEALRTAPPAAPLAGLYYGTLGTPGPYPGPLSPPPEAPPLESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG
  
Inhibitor
Name:
BDBM22971
Synonyms:
2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid | CHEMBL509 | Meclofenamate | Meclofenamic acid | US11337935, Compound Meclofenamic-acid | US20240002326, Compound Meclofenamic acid
Type:
Small organic molecule
Emp. Form.:
C14H11Cl2NO2
Mol. Mass.:
296.149
SMILES:
Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl
Structure:
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