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Target
Bromodomain-containing protein 4 [368-440]
Ligand
BDBM179457
Substrate
n/a
Meas. Tech.
FP Competitive Binding Assay (BRD-1F)
pH
7.5000±n/a
Temperature
298.1500±n/a K
Ki
83±n/a nM
IC50
514±n/a nM
Comments
extracted
Citation
 Wang, S; Ran, X; Zhao, Y; Yang, C; Liu, L; Bai, L; McEachern, D; Stuckey, J; Meagher, JL; Sun, D; Li, X; Zhou, B; Karatas, H; Luo, R; Chinnaiyan, A; Asangani, IA BET bromodomain inhibitors and therapeutic methods using the same US Patent  US9675697 Publication Date 6/13/2017 
Target
Name:
Bromodomain-containing protein 4 [368-440]
Synonyms:
Bromodomain-containing protein 4 Bromo 2 domain(BRD4 BD2) | Bromodomain-containing protein 4 (BRD4) Bromo 2 | Bromodomain-containing protein 4 (BRD4)(BD2) | Bromodomain-containing protein 4 (BRD4)(Bromo 2) | Bromodomain-containing protein 4 Bromodomain 2 (BRD4-2) | Bromodomain-containing protein 4 Domain 2 | Bromo domain 2 | Bromodomain-containing protein 4 (BD2) | BRD4_HUMAN | BRD4 | HUNK1
Type:
Protein
Mol. Mass.:
8564.63
Organism:
Human
Description:
BD2 (368-440 aa) of O60885
Residue:
73
Sequence:
KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVV
  
Inhibitor
Name:
BDBM179457
Synonyms:
US9675697, Cpd. No. 3
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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