Reaction Details
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Interleukin-21
Ligand
BDBM649494
Substrate
n/a
Meas. Tech.
IL-21 ALPHALISA assay
IC50
42.6±n/a nM
Citation
Colabuono, P; Johnson, G; Manning, DD; Wolf, MA Indole compounds and their use US Patent US11891386 Publication Date 2/6/2024 More Info.:
Target
Name:
Interleukin-21
Synonyms:
IL21 | IL21_HUMAN | Za11 | il-21
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17933.60
Organism:
Homo sapiens (Human)
Description:
Q9HBE4
Residue:
162
Sequence:
MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
Inhibitor
Name:
BDBM649494
Synonyms:
US11891386, Compound ARI-031
Type:
Small organic molecule
Emp. Form.:
C15H10N4O2S
Mol. Mass.:
310.331
SMILES:
Cc1noc(n1)-c1csc(n1)C(=O)c1c[nH]c2ccccc12
Structure:
