Reaction Details Report a problem with these data
Target
G-protein coupled receptor 52
Ligand
BDBM50554908
Substrate
n/a
Meas. Tech.
Glosensor cAMP assay
EC50
275±13 nM
Citation
 ZHOU, J; ALLEN, JA; WANG, P; FELSING, DE HETEROCYCLIC G-PROTEIN-COUPLED RECEPTOR 52 (GPR52) AGONISTS US Patent  US20240059655 Publication Date 2/22/2024 
Target
Name:
G-protein coupled receptor 52
Synonyms:
G-protein coupled receptor 52 | GPR52_MOUSE | Gpr52
Type:
PROTEIN
Mol. Mass.:
41353.59
Organism:
Mus musculus
Description:
ChEMBL_117396
Residue:
361
Sequence:
MNESRWTEWRILNMSSSIVNVSEHHSCPLGFGHYSVEDVCIFETVVIVLLTFLIISGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLLVGVTCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIIMIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTCFIVCLLYAPAALVVCFTYFHIFKICRQHTKEINDRRARFPSHEVEASREAGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCVCAKDQEAQDPKPRRRANSCSI
  
Inhibitor
Name:
BDBM50554908
Synonyms:
CHEMBL4740473 | US20240059655, Compound PW0938
Type:
Small organic molecule
Emp. Form.:
C24H22F4N4O2
Mol. Mass.:
474.4507
SMILES:
OCCCNC(=O)c1cccc2N(CCc12)c1cc(Cc2cc(F)cc(c2)C(F)(F)F)ncn1
Structure:
Search PDB for entries with ligand similarity: