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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM317227
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
40.0±n/a nM
Citation
 Alcalde-Pais, M; Diaz Fernández, JL; Mesquida-Estevez, M; Paloma-Romeu, L Imidazo[2,1-b]thiazole derivatives, their preparation and use as medicaments US Patent  US9617281 Publication Date 4/11/2017 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM317227
Synonyms:
6-((2-(Azepan-1- ylethoxy)methyl)-2- phenylimidazo[2,1- b]thiazole maleate | US9617281, Compound 9
Type:
Small organic molecule
Emp. Form.:
C20H25N3OS
Mol. Mass.:
355.497
SMILES:
C(CN1CCCCCC1)OCc1cn2cc(sc2n1)-c1ccccc1
Structure:
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