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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM317229
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
260±n/a nM
Citation
 Alcalde-Pais, M; Diaz Fernández, JL; Mesquida-Estevez, M; Paloma-Romeu, L Imidazo[2,1-b]thiazole derivatives, their preparation and use as medicaments US Patent  US9617281 Publication Date 4/11/2017 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM317229
Synonyms:
6-((4- Methylpiperazin-1- ylmethyl)-2- phenylimidazo[2,1- b][1,3,4]thiadiazole maleate | US9617281, Compound 11
Type:
Small organic molecule
Emp. Form.:
C16H19N5S
Mol. Mass.:
313.421
SMILES:
CN1CCN(Cc2cn3nc(sc3n2)-c2ccccc2)CC1
Structure:
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