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Target
Capsid protein
Ligand
BDBM324423
Substrate
n/a
Meas. Tech.
BDNA-assay
EC50
<500±n/a nM
Citation
 Hartman, GD; Kuduk, S Derivatives and methods of treating hepatitis B infections US Patent  US10189835 Publication Date 1/29/2019 
Target
Name:
Capsid protein
Synonyms:
C | CAPSD_HBVCJ | Core antigen | Core protein | HBcAg | p21.5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21105.01
Organism:
Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-) (HBV-C)
Description:
n/a
Residue:
183
Sequence:
MDIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
  
Inhibitor
Name:
BDBM324423
Synonyms:
US10189835, Compound 699
Type:
Small organic molecule
Emp. Form.:
C17H18ClN5O3
Mol. Mass.:
375.81
SMILES:
Clc1cccc(NC(=O)N2CCc3[nH]nc(C(=O)N4CCCO4)c3C2)c1
Structure:
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