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Target
Retinaldehyde-binding protein 1
Ligand
BDBM338936
Substrate
n/a
Meas. Tech.
Isomerase Assay
IC50
<1000±n/a nM
Citation
 Scott, IL; Kuksa, VA; Gall, A; Orme, MW; Gage, J; Little, Jr., TL; Jiang, Q; Rossiter, LM; McGee, Jr., KF; Kubota, R Styrenyl derivative compounds for treating ophthalmic diseases and disorders US Patent  US10201545 Publication Date 2/12/2019 
Target
Name:
Retinaldehyde-binding protein 1
Synonyms:
CRALBP | Cellular retinaldehyde-binding protein | RLBP1 | RLBP1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36462.25
Organism:
Homo sapiens (Human)
Description:
P12271
Residue:
317
Sequence:
MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLFGPQAQAENTAF
  
Inhibitor
Name:
BDBM338936
Synonyms:
(E)-3-amino-2-methyl-1-(3-(2-(2,6,6-trimethylcyclohex- 1-enyl)vinyl)phenyl)propan-1-one | US10201545, Compound 72
Type:
Small organic molecule
Emp. Form.:
C21H29NO
Mol. Mass.:
311.4611
SMILES:
CC(CN)C(=O)c1cccc(\C=C\C2=C(C)CCCC2(C)C)c1 |c:13|
Structure:
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