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Target
Retinaldehyde-binding protein 1
Ligand
BDBM338978
Substrate
n/a
Meas. Tech.
Isomerase Assay
IC50
<10000±n/a nM
Citation
 Scott, IL; Kuksa, VA; Gall, A; Orme, MW; Gage, J; Little, Jr., TL; Jiang, Q; Rossiter, LM; McGee, Jr., KF; Kubota, R Styrenyl derivative compounds for treating ophthalmic diseases and disorders US Patent  US10201545 Publication Date 2/12/2019 
Target
Name:
Retinaldehyde-binding protein 1
Synonyms:
CRALBP | Cellular retinaldehyde-binding protein | RLBP1 | RLBP1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36462.25
Organism:
Homo sapiens (Human)
Description:
P12271
Residue:
317
Sequence:
MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLFGPQAQAENTAF
  
Inhibitor
Name:
BDBM338978
Synonyms:
(E/Z)-N-(3-(3-(2,6-dimethylstyryl)phenyl)prop- yl)acetamide | US10201545, Compound 51
Type:
Small organic molecule
Emp. Form.:
C21H25NO
Mol. Mass.:
307.4293
SMILES:
CC(=O)NCCCc1cccc(C=Cc2c(C)cccc2C)c1 |w:12.11|
Structure:
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