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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM615617
Substrate
n/a
Meas. Tech.
Tag-Lite Binding Assay
Ki
68.4±n/a nM
Citation
 Liang, B; Yang, Y; Wang, P; Yang, B; Lai, Y; Wu, JJ GLP-1R MODULATING COMPOUNDS US Patent  US20230271949 Publication Date 8/31/2023 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1)
Type:
Enzyme
Mol. Mass.:
53035.78
Organism:
Homo sapiens (Human)
Description:
P43220
Residue:
463
Sequence:
MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM615617
Synonyms:
US20230271949, Example 408
Type:
Small organic molecule
Emp. Form.:
C40H36ClF2N9O2
Mol. Mass.:
748.223
SMILES:
CCn1cncc1Cn1c(CN2CCC(=CC2)c2cccc(OCc3ccc(Cl)cc3F)n2)nc2cc(NC(=O)c3cc(F)c4[nH]nc(C)c4c3)ccc12 |c:15|
Structure:
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