Reaction Details Report a problem with these data
Target
P2Y purinoceptor 13
Ligand
BDBM359087
Substrate
n/a
Meas. Tech.
Ca++ flux assay
EC50
298700±n/a nM
Citation
 Dasseux, JH; Barbaras, R Compounds, compositions and methods useful for cholesterol mobilization US Patent  US10220040 Publication Date 3/5/2019 
Target
Name:
P2Y purinoceptor 13
Synonyms:
G-protein coupled receptor 86 | G-protein coupled receptor 94 | GPR86 | GPR94 | P2RY13 | P2Y13 | P2Y13_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40817.42
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
354
Sequence:
MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG
  
Inhibitor
Name:
BDBM359087
Synonyms:
US10220040, Compound IIb
Type:
Small organic molecule
Emp. Form.:
C22H30N4O3
Mol. Mass.:
398.4986
SMILES:
COc1ccc(CN2CCC(CC2)c2cc(O)nc(n2)N2CCCCC2)cc1O
Structure:
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