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Target
Interleukin-21
Ligand
BDBM247029
Substrate
n/a
IC50
<10000±n/a nM
Citation
 Gaweco, A; Tilley, J; Blinn, J Sulfonamide retinoic acid receptor-related orphan receptor modulators and uses thereof US Patent  US9701663 Publication Date 7/11/2017 
Target
Name:
Interleukin-21
Synonyms:
IL21 | IL21_HUMAN | Za11 | il-21
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17933.60
Organism:
Homo sapiens (Human)
Description:
Q9HBE4
Residue:
162
Sequence:
MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
  
Inhibitor
Name:
BDBM247029
Synonyms:
1-((1-(4-chlorophenylsulfonyl)piperidin-4-yl)methyl)-5-(1H-pyrazol-4-yl)-1H-indole | US9701663, 36
Type:
Small organic molecule
Emp. Form.:
C23H23ClN4O2S
Mol. Mass.:
454.972
SMILES:
Clc1ccc(cc1)S(=O)(=O)N1CCC(Cn2ccc3cc(ccc23)-c2cn[nH]c2)CC1
Structure:
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