Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM31083
Substrate
Not Available
Meas. Tech.
Dose Response Assay for Agonists of 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1A (5HT1A)
pH
7.4±n/a
Temperature
296.15±n/a K
IC50
7334±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1A (5HT1A) PubChem Bioassay (2007)[AID] 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM31083
Synonyms:
MLS000107813 | SMR000103777 | [4-(4,7-dimethyl-1,3-dioxo-3a,7a-dihydro-octahydro-1H-4,7-epoxyisoindol-2-yl)phenyl] acetate | [4-[4,7-dimethyl-1,3-bis(oxidanylidene)-3a,7a-dihydro-octahydro-1H-4,7-epoxyisoindol-2-yl]phenyl] ethanoate | acetic acid [4-(1,3-diketo-4,7-dimethyl-3a,7a-dihydro-octahydro-1H-4,7-epoxyisoindol-2-yl)phenyl] ester | acetic acid [4-(4,7-dimethyl-1,3-dioxo-3a,7a-dihydro-octahydro-1H-4,7-epoxyisoindol-2-yl)phenyl] ester | cid_2860584
Type:
Small organic molecule
Emp. Form.:
C18H17NO5
Mol. Mass.:
327.3313
SMILES:
CC(=O)Oc1ccc(cc1)-n1c(O)c2c(c1O)C1(C)OC2(C)C=C1 |c:25,TLB:15:14:19:22.23,THB:11:13:19:22.23|
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
Not Available
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA