Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1E
Ligand
BDBM31027
Substrate
Not Available
Meas. Tech.
Dose Response Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E)
pH
7.4±n/a
Temperature
296.15±n/a K
EC50
1832±n/a nM
Citation
 PubChem, PC Dose Response Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) PubChem Bioassay (2007)[AID] 
Target
Name:
5-hydroxytryptamine receptor 1E
Synonyms:
5-HT-1E | 5-HT1E | 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) | 5-hydroxytryptamine receptor 1E | 5-hydroxytryptamine receptor 1E (5-HT-1E) (S31) | 5-hydroxytryptamine receptor 1E (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31). | 5HT1E_HUMAN | HTR1E | S31 | Serotonin (5-HT) receptor | Serotonin 1e (5-HT1e) receptor | Serotonin Receptor 1E
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41697.80
Organism:
Homo sapiens (Human)
Description:
gi_112822
Residue:
365
Sequence:
MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
  
Inhibitor
Name:
BDBM31027
Synonyms:
1-[[5-[[butyl(ethyl)amino]methyl]-2-furanyl]methyl]-3-(2,4-dimethoxyphenyl)urea | 1-[[5-[[butyl(ethyl)amino]methyl]-2-furyl]methyl]-3-(2,4-dimethoxyphenyl)urea | 1-[[5-[[butyl(ethyl)amino]methyl]furan-2-yl]methyl]-3-(2,4-dimethoxyphenyl)urea | MLS000046660 | N-[(5-{[butyl(ethyl)amino]methyl}-2-furyl)methyl]-N'-(2,4-dimethoxyphenyl)urea | SMR000032671 | cid_3240509
Type:
Small organic molecule
Emp. Form.:
C21H31N3O4
Mol. Mass.:
389.4885
SMILES:
CCCCN(CC)Cc1ccc(CNC(=O)Nc2ccc(OC)cc2OC)o1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
Not Available
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA