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Target
Kappa-type opioid receptor
Ligand
BDBM397988
Substrate
n/a
Meas. Tech.
Radioligand dose-displacement Binding Assay
Ki
>20000±n/a nM
Citation
 Tafesse, L 10-substituted morphinan hydantoins US Patent  US9994571 Publication Date 6/12/2018 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM397988
Synonyms:
US9994571, Compound 12
Type:
Small organic molecule
Emp. Form.:
C20H25N3O5
Mol. Mass.:
387.4296
SMILES:
COc1ccc2[C@@H](O)[C@H]3N(C)CC[C@@]4(C[C@]5(CC[C@@]34O)NC(=O)NC5=O)c2c1 |r|
Structure:
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