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Target
Mu-type opioid receptor
Ligand
BDBM397991
Substrate
n/a
Meas. Tech.
Radioligand dose-displacement Binding Assay
Ki
15408±3126 nM
Citation
 Tafesse, L 10-substituted morphinan hydantoins US Patent  US9994571 Publication Date 6/12/2018 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM397991
Synonyms:
US9994571, Compound 15
Type:
Small organic molecule
Emp. Form.:
C22H23N3O6
Mol. Mass.:
425.4345
SMILES:
Oc1ccc2c3c1O[C@H]1[C@]4(CC[C@@]5(O)[C@H](N(CC6CC6)CC[C@]315)C2=O)NC(=O)NC4=O |r|
Structure:
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