Target

Ligand

Substrate

Meas. Tech.

HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate

pH

7.4±n/a

Temperature

296.15±n/a K

Citation

 PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate PubChem Bioassay (2009)[AID] Copy BDB DOI

More Info.:

Get all data from this article,   Solution Info,  Assay Method

Name:

Mannose-6-phosphate isomerase

Synonyms:

MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1

Type:

PROTEIN

Mol. Mass.:

46651.35

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1448919

Residue:

423

Sequence:

MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM29644

Synonyms:

(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride | APOMORPHINE HYDROCHLORIDE | APOMORPHINE HYDROCHLORIDE HEMIHYDRATE | MLS000069811 | SMR000059235 | cid_6852399

Type:

Small organic molecule

Emp. Form.:

C17H17NO2

Mol. Mass.:

267.3224

SMILES:

CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

Mannose-6-phosphate

Synonyms:

n/a

Type:

n/a

Mol. Mass.:

358.43

Organism:

n/a

Description:

n/a

Residue:

3

Sequence:

NA