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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM37071
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
30500±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM37071
Synonyms:
1-(1,3-benzodioxol-5-ylmethyl)-4-[({[5-methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}thio)acetyl]piperazine | 1-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-2-[[5-methyl-2-(3-methylphenyl)-4-oxazolyl]methylthio]ethanone | 1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-2-[[5-methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methylsulfanyl]ethanone | 2-[[5-methyl-2-(m-tolyl)oxazol-4-yl]methylthio]-1-(4-piperonylpiperazino)ethanone | MLS000046831 | SMR000032842 | cid_3242691
Type:
Small organic molecule
Emp. Form.:
C26H29N3O4S
Mol. Mass.:
479.591
SMILES:
Cc1oc(nc1CSCC(=O)N1CCN(Cc2ccc3OCOc3c2)CC1)-c1cccc(C)c1
Structure:
Search PDB for entries with ligand similarity: