Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM34341
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
12370±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM34341
Synonyms:
3-[3-(4-fluorophenyl)-7-methyl-1-(1-pyrrolidinyl)-1-sulfanylidene-5-pyrazolo[4,3-c][1,5,2]oxazaphosphorinyl]propanenitrile | 3-[3-(4-fluorophenyl)-7-methyl-1-pyrrolidin-1-yl-1-sulfanylidene-pyrazolo[4,3-c][1,5,2]oxazaphosphinin-5-yl]propanenitrile | 3-[3-(4-fluorophenyl)-7-methyl-1-pyrrolidin-1-yl-1-sulfanylidenepyrazolo[4,3-c][1,5,2]oxazaphosphinin-5-yl]propanenitrile | 3-[3-(4-fluorophenyl)-7-methyl-1-pyrrolidino-1-thioxo-pyrazolo[4,3-c][1,5,2]oxazaphosphorin-5-yl]propionitrile | MLS000055028 | SMR000065836 | cid_2320436
Type:
Small organic molecule
Emp. Form.:
C18H19FN5OPS
Mol. Mass.:
403.414
SMILES:
Cc1nn(CCC#N)c2N=C(OP(=S)(N3CCCC3)c12)c1ccc(F)cc1 |c:9|
Structure:
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