Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM32790
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>16600±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM32790
Synonyms:
2-({[(4-chlorophenyl)amino]carbonyl}amino)-N-(2-furylmethyl)benzamide | 2-[(4-chlorophenyl)carbamoylamino]-N-(2-furfuryl)benzamide | 2-[(4-chlorophenyl)carbamoylamino]-N-(furan-2-ylmethyl)benzamide | 2-[[(4-chloroanilino)-oxomethyl]amino]-N-(2-furanylmethyl)benzamide | MLS000051886 | SMR000081021 | cid_1131627
Type:
Small organic molecule
Emp. Form.:
C19H16ClN3O3
Mol. Mass.:
369.802
SMILES:
Clc1ccc(NC(=O)Nc2ccccc2C(=O)NCc2ccco2)cc1
Structure:
Search PDB for entries with ligand similarity: