Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37442
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>49800±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37442
Synonyms:
MLS000063716 | N-(2-furanyl)-3-[(1-oxo-2-thiophen-2-ylethyl)amino]benzamide | N-(2-furyl)-3-[[2-(2-thienyl)acetyl]amino]benzamide | N-(furan-2-yl)-3-(2-thiophen-2-ylethanoylamino)benzamide | N-(furan-2-yl)-3-[(2-thiophen-2-ylacetyl)amino]benzamide | N-2-furyl-3-[(2-thienylacetyl)amino]benzamide | SMR000075462 | cid_976770
Type:
Small organic molecule
Emp. Form.:
C17H14N2O3S
Mol. Mass.:
326.37
SMILES:
O=C(Cc1cccs1)Nc1cccc(c1)C(=O)Nc1ccco1
Structure:
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