Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37453
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>16600±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37453
Synonyms:
2-(3-chloro-4-methoxy-anilino)-6-propyl-1H-pyrimidin-4-one | 2-(3-chloro-4-methoxyanilino)-6-propyl-1H-pyrimidin-4-one | 2-[(3-chloranyl-4-methoxy-phenyl)amino]-6-propyl-1H-pyrimidin-4-one | 2-[(3-chloro-4-methoxyphenyl)amino]-6-propyl-4(3H)-pyrimidinone | MLS000065526 | SMR000080114 | cid_734787
Type:
Small organic molecule
Emp. Form.:
C14H16ClN3O2
Mol. Mass.:
293.749
SMILES:
CCCc1cc(=O)[nH]c(Nc2ccc(OC)c(Cl)c2)n1
Structure:
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