Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37484
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>49800±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37484
Synonyms:
1-cyclopentyl-5-oxidanylidene-N-[3-[4-(phenylmethyl)piperidin-1-yl]propyl]pyrrolidine-3-carboxamide | 1-cyclopentyl-5-oxo-N-[3-[4-(phenylmethyl)-1-piperidinyl]propyl]-3-pyrrolidinecarboxamide | MLS000120149 | N-[3-(4-benzylpiperidin-1-yl)propyl]-1-cyclopentyl-5-oxopyrrolidine-3-carboxamide | N-[3-(4-benzylpiperidino)propyl]-1-cyclopentyl-5-keto-pyrrolidine-3-carboxamide | SMR000097066 | cid_5309860
Type:
Small organic molecule
Emp. Form.:
C25H37N3O2
Mol. Mass.:
411.5802
SMILES:
O=C(NCCCN1CCC(Cc2ccccc2)CC1)C1CN(C2CCCC2)C(=O)C1
Structure:
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