Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37608
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
>43700±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37608
Synonyms:
3-(furan-2-carbonyl)-4-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-(2-phenylethyl)-2H-pyrrol-5-one | 3-(furan-2-ylcarbonyl)-2-(3-methoxy-4-oxidanyl-phenyl)-4-oxidanyl-1-(2-phenylethyl)-2H-pyrrol-5-one | 3-[2-furanyl(oxo)methyl]-4-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-(2-phenylethyl)-2H-pyrrol-5-one | 4-(2-furoyl)-3-hydroxy-5-(4-hydroxy-3-methoxy-phenyl)-1-phenethyl-3-pyrrolin-2-one | 4-(Furan-2-carbonyl)-3-hydroxy-5-(4-hydroxy-3-methoxy-phenyl)-1-phenethyl-1,5-dihydro-pyrrol-2-one | MLS000034764 | SMR000013494 | cid_647552
Type:
Small organic molecule
Emp. Form.:
C24H21NO6
Mol. Mass.:
419.4266
SMILES:
COc1cc(ccc1O)C1C(C(=O)c2ccco2)C(=O)C(=O)N1CCc1ccccc1
Structure:
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