Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37660
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
37800±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37660
Synonyms:
(4Z)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(furan-2-yl)pyrrolidine-2,3-dione | (4Z)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)-oxidanyl-methylidene]-5-(furan-2-yl)pyrrolidine-2,3-dione | (4Z)-1-(4,5-dimethyl-2-thiazolyl)-4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(2-furanyl)pyrrolidine-2,3-dione | (4Z)-1-(4,5-dimethylthiazol-2-yl)-5-(2-furyl)-4-[hydroxy(p-phenetyl)methylene]pyrrolidine-2,3-quinone | MLS000081062 | SMR000058132 | cid_5389606
Type:
Small organic molecule
Emp. Form.:
C22H20N2O5S
Mol. Mass.:
424.47
SMILES:
CCOc1ccc(cc1)C(=O)C1C(N(C(=O)C1=O)c1nc(C)c(C)s1)c1ccco1
Structure:
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