Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37662
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
IC50
21400±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37662
Synonyms:
1-[2-(2-hydroxyethyloxy)ethyl]-4-oxidanyl-2-thiophen-2-yl-3-thiophen-2-ylcarbonyl-2H-pyrrol-5-one | 3-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-4-(2-thenoyl)-5-(2-thienyl)-3-pyrrolin-2-one | 4-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-3-(thiophene-2-carbonyl)-2-thiophen-2-yl-2H-pyrrol-5-one | 4-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-3-[oxo(thiophen-2-yl)methyl]-2-thiophen-2-yl-2H-pyrrol-5-one | MLS000040265 | SMR000059740 | cid_663185
Type:
Small organic molecule
Emp. Form.:
C17H17NO5S2
Mol. Mass.:
379.451
SMILES:
OCCOCCN1C(C(C(=O)c2cccs2)C(=O)C1=O)c1cccs1
Structure:
Search PDB for entries with ligand similarity: