Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM37604
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
Ki
>40300±n/a nM
Comments
Extracted from aid = 520 and tid = 2
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM37604
Synonyms:
2-[4-Ethyl-5-(3-hydroxy-naphthalen-2-yl)-4H-[1,2,4]triazol-3-ylsulfanyl]-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-acetamide | 2-[[(5E)-4-ethyl-5-(3-keto-2-naphthylidene)-1H-1,2,4-triazol-3-yl]thio]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide | 2-[[(5E)-4-ethyl-5-(3-oxidanylidenenaphthalen-2-ylidene)-1H-1,2,4-triazol-3-yl]sulfanyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)ethanamide | 2-[[(5E)-4-ethyl-5-(3-oxo-2-naphthalenylidene)-1H-1,2,4-triazol-3-yl]thio]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide | 2-[[(5E)-4-ethyl-5-(3-oxonaphthalen-2-ylidene)-1H-1,2,4-triazol-3-yl]sulfanyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide | MLS000032897 | SMR000002531 | cid_5892268
Type:
Small organic molecule
Emp. Form.:
C20H20N6O2S2
Mol. Mass.:
440.542
SMILES:
CCc1nnc(NC(=O)CSc2nnc(-c3cc4ccccc4cc3O)n2CC)s1
Structure:
Search PDB for entries with ligand similarity: