Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM37616
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
Ki
>40300±n/a nM
Comments
Extracted from aid = 520 and tid = 2
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM37616
Synonyms:
2-(3-methoxy-4-oxidanyl-phenyl)-3-(5-methylfuran-2-yl)carbonyl-4-oxidanyl-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one | 3-Hydroxy-5-(4-hydroxy-3-methoxy-phenyl)-4-(5-methyl-furan-2-carbonyl)-1-pyridin-3-ylmethyl-1,5-dihydro-pyrrol-2-one | 3-hydroxy-5-(4-hydroxy-3-methoxy-phenyl)-4-(5-methyl-2-furoyl)-1-(3-pyridylmethyl)-3-pyrrolin-2-one | 4-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(5-methylfuran-2-carbonyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one | 4-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-[(5-methyl-2-furanyl)-oxomethyl]-1-(3-pyridinylmethyl)-2H-pyrrol-5-one | MLS000075388 | SMR000012181 | cid_652064
Type:
Small organic molecule
Emp. Form.:
C23H20N2O6
Mol. Mass.:
420.4147
SMILES:
COc1cc(ccc1O)C1C(C(=O)c2ccc(C)o2)C(=O)C(=O)N1Cc1cccnc1
Structure:
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