Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM37625
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
Ki
>40300±n/a nM
Comments
Extracted from aid = 520 and tid = 2
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM37625
Synonyms:
(4Z)-1-(2-furfuryl)-4-[hydroxy(m-phenetyl)methylene]-5-(4-pyridyl)pyrrolidine-2,3-quinone | (4Z)-4-[(3-ethoxyphenyl)-hydroxymethylidene]-1-(2-furanylmethyl)-5-pyridin-4-ylpyrrolidine-2,3-dione | (4Z)-4-[(3-ethoxyphenyl)-hydroxymethylidene]-1-(furan-2-ylmethyl)-5-pyridin-4-ylpyrrolidine-2,3-dione | (4Z)-4-[(3-ethoxyphenyl)-oxidanyl-methylidene]-1-(furan-2-ylmethyl)-5-pyridin-4-yl-pyrrolidine-2,3-dione | 4-(3-Ethoxy-benzoyl)-1-furan-2-ylmethyl-3-hydroxy-5-pyridin-4-yl-1,5-dihydro-pyrrol-2-one | MLS000033794 | SMR000013592 | cid_6398932
Type:
Small organic molecule
Emp. Form.:
C23H20N2O5
Mol. Mass.:
404.4153
SMILES:
CCOc1cccc(c1)C(=O)C1C(N(Cc2ccco2)C(=O)C1=O)c1ccncc1
Structure:
Search PDB for entries with ligand similarity: