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Target
Mevalonate kinase
Ligand
BDBM38768
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
96214.4±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38768
Synonyms:
1-[2-[2-(2-bromanyl-4-methyl-phenoxy)ethoxy]ethyl]imidazole | 1-[2-[2-(2-bromo-4-methyl-phenoxy)ethoxy]ethyl]imidazole | 1-[2-[2-(2-bromo-4-methylphenoxy)ethoxy]ethyl]imidazole | MLS000113166 | SMR000109072 | cid_2923447
Type:
Small organic molecule
Emp. Form.:
C14H17BrN2O2
Mol. Mass.:
325.201
SMILES:
Cc1ccc(OCCOCCn2ccnc2)c(Br)c1
Structure:
Search PDB for entries with ligand similarity: