Reaction Details Report a problem with these data
Target
Mevalonate kinase
Ligand
BDBM38607
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
29822.1±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38607
Synonyms:
4-[(6-benzyl-5-keto-7H-pyrrolo[3,4-b]pyridin-7-yl)amino]-N,N-diethyl-benzenesulfonamide | 4-[(6-benzyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-7-yl)amino]-N,N-diethylbenzenesulfonamide | 4-[(6-benzyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-7-yl)amino]-N,N-diethylbenzenesulfonamide | MLS000045757 | N,N-diethyl-4-[[5-oxidanylidene-6-(phenylmethyl)-7H-pyrrolo[3,4-b]pyridin-7-yl]amino]benzenesulfonamide | N,N-diethyl-4-[[5-oxo-6-(phenylmethyl)-7H-pyrrolo[3,4-b]pyridin-7-yl]amino]benzenesulfonamide | SMR000028153 | cid_3241332
Type:
Small organic molecule
Emp. Form.:
C24H26N4O3S
Mol. Mass.:
450.553
SMILES:
CCN(CC)S(=O)(=O)c1ccc(Nc2n(Cc3ccccc3)c(=O)c3ccc[nH]c23)cc1
Structure:
Search PDB for entries with ligand similarity: