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Target
Dual specificity protein phosphatase 6
Ligand
BDBM35416
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35416
Synonyms:
5-({4-[2-cyano-2-(4-fluorophenyl)vinyl]-2-methoxyphenoxy}methyl)-2-furoic acid | 5-[[4-[(E)-2-cyano-2-(4-fluorophenyl)ethenyl]-2-methoxy-phenoxy]methyl]furan-2-carboxylic acid | 5-[[4-[(E)-2-cyano-2-(4-fluorophenyl)ethenyl]-2-methoxyphenoxy]methyl]-2-furancarboxylic acid | 5-[[4-[(E)-2-cyano-2-(4-fluorophenyl)ethenyl]-2-methoxyphenoxy]methyl]furan-2-carboxylic acid | 5-[[4-[(E)-2-cyano-2-(4-fluorophenyl)vinyl]-2-methoxy-phenoxy]methyl]-2-furoic acid | MLS000051640 | SMR000080179 | cid_1243762
Type:
Small organic molecule
Emp. Form.:
C22H16FNO5
Mol. Mass.:
393.3645
SMILES:
COc1cc(\C=C(\C#N)c2ccc(F)cc2)ccc1OCc1ccc(o1)C(O)=O
Structure:
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