Reaction Details Report a problem with these data
Target
M-phase inducer phosphatase 2
Ligand
BDBM38795
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2006)[AID] 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM38795
Synonyms:
4-phenyl-N-[3-[(4-phenylpiperazin-1-yl)carbonylamino]phenyl]piperazine-1-carboxamide | 4-phenyl-N-[3-[(4-phenylpiperazine-1-carbonyl)amino]phenyl]piperazine-1-carboxamide | MLS000068850 | N-[3-[[oxo-(4-phenyl-1-piperazinyl)methyl]amino]phenyl]-4-phenyl-1-piperazinecarboxamide | SMR000008895 | cid_647933
Type:
Small organic molecule
Emp. Form.:
C28H32N6O2
Mol. Mass.:
484.5927
SMILES:
O=C(Nc1cccc(NC(=O)N2CCN(CC2)c2ccccc2)c1)N1CCN(CC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: