Reaction Details Report a problem with these data
Target
M-phase inducer phosphatase 2
Ligand
BDBM38799
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2006)[AID] 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM38799
Synonyms:
4-(2,4-Dichloro-phenoxy)-N-(5-methyl-isoxazol-3-yl)-butyramide | 4-(2,4-dichlorophenoxy)-N-(5-methyl-1,2-oxazol-3-yl)butanamide | 4-(2,4-dichlorophenoxy)-N-(5-methyl-3-isoxazolyl)butanamide | 4-(2,4-dichlorophenoxy)-N-(5-methylisoxazol-3-yl)butyramide | 4-[2,4-bis(chloranyl)phenoxy]-N-(5-methyl-1,2-oxazol-3-yl)butanamide | MLS000075082 | SMR000011787 | cid_653219
Type:
Small organic molecule
Emp. Form.:
C14H14Cl2N2O3
Mol. Mass.:
329.179
SMILES:
Cc1cc(NC(=O)CCCOc2ccc(Cl)cc2Cl)no1
Structure:
Search PDB for entries with ligand similarity: