Reaction Details Report a problem with these data
Target
M-phase inducer phosphatase 2
Ligand
BDBM38840
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2006)[AID] 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM38840
Synonyms:
MLS000118476 | N-(2-furanylmethyl)-3-methyl-2-[(2-methyl-1,3-benzothiazol-6-yl)sulfonylamino]butanamide | N-(2-furfuryl)-3-methyl-2-[(2-methyl-1,3-benzothiazol-6-yl)sulfonylamino]butyramide | N-(furan-2-ylmethyl)-3-methyl-2-[(2-methyl-1,3-benzothiazol-6-yl)sulfonylamino]butanamide | SMR000095417 | cid_5309266
Type:
Small organic molecule
Emp. Form.:
C18H21N3O4S2
Mol. Mass.:
407.507
SMILES:
CC(C)C(NS(=O)(=O)c1ccc2nc(C)sc2c1)C(=O)NCc1ccco1
Structure:
Search PDB for entries with ligand similarity: