Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM37108
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1)
IC50
108±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM37108
Synonyms:
5-bromanyl-N-(pyridin-4-ylmethyl)thiophene-2-sulfonamide | 5-bromo-N-(4-pyridinylmethyl)-2-thiophenesulfonamide | 5-bromo-N-(4-pyridylmethyl)thiophene-2-sulfonamide | 5-bromo-N-(pyridin-4-ylmethyl)-2-thiophenesulfonamide | 5-bromo-N-(pyridin-4-ylmethyl)thiophene-2-sulfonamide | MLS000063220 | SMR000074767 | cid_936105
Type:
Small organic molecule
Emp. Form.:
C10H9BrN2O2S2
Mol. Mass.:
333.225
SMILES:
Brc1ccc(s1)S(=O)(=O)NCc1ccncc1
Structure:
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