Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM39456
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1)
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM39456
Synonyms:
(2-ethylbenzofuro[3,2-d]pyrimidin-4-yl)-quinoxalin-6-yl-amine;hydrochloride | 2-ethyl-N-(6-quinoxalinyl)-4-benzofuro[3,2-d]pyrimidinamine;hydrochloride | 2-ethyl-N-quinoxalin-6-yl-[1]benzofuro[3,2-d]pyrimidin-4-amine;hydrochloride | MLS000041713 | SMR000044796 | cid_6602826
Type:
Small organic molecule
Emp. Form.:
C20H15N5O
Mol. Mass.:
341.366
SMILES:
CCc1nc(Nc2ccc3nccnc3c2)c2oc3ccccc3c2n1
Structure:
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