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Target
Procathepsin L
Ligand
BDBM41135
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41135
Synonyms:
7-[3-(4-chloranylphenoxy)-2-oxidanyl-propyl]-8-[2-(dimethylamino)ethylamino]-3-methyl-purine-2,6-dione | 7-[3-(4-chlorophenoxy)-2-hydroxy-propyl]-8-[2-(dimethylamino)ethylamino]-3-methyl-xanthine | 7-[3-(4-chlorophenoxy)-2-hydroxypropyl]-8-[2-(dimethylamino)ethylamino]-3-methylpurine-2,6-dione | MLS000037520 | SMR000057821 | cid_659326
Type:
Small organic molecule
Emp. Form.:
C19H25ClN6O4
Mol. Mass.:
436.893
SMILES:
CN(C)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc1ccc(Cl)cc1
Structure:
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