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Target
Cathepsin S
Ligand
BDBM41290
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41290
Synonyms:
2-(3-Methoxy-4-tetrazol-1-yl-benzenesulfonyl)-2-aza-spiro[5.5]undecane | 2-[3-methoxy-4-(1,2,3,4-tetrazol-1-yl)phenyl]sulfonyl-2-azaspiro[5.5]undecane | 2-[3-methoxy-4-(1-tetrazolyl)phenyl]sulfonyl-2-azaspiro[5.5]undecane | 2-[3-methoxy-4-(tetrazol-1-yl)phenyl]sulfonyl-2-azaspiro[5.5]undecane | MLS000031091 | SMR000003717 | cid_653456
Type:
Small organic molecule
Emp. Form.:
C18H25N5O3S
Mol. Mass.:
391.488
SMILES:
COc1cc(ccc1-n1cnnn1)S(=O)(=O)N1CCCC2(CCCCC2)C1
Structure:
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