Reaction Details Report a problem with these data
Target
Cathepsin S
Ligand
BDBM41301
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41301
Synonyms:
6-fluoranyl-3-[1,1,2,3,3,3-hexakis(fluoranyl)propylsulfanyl]-2-methyl-1H-quinolin-4-one | 6-fluoro-3-(1,1,2,3,3,3-hexafluoropropylsulfanyl)-2-methyl-1H-quinolin-4-one | 6-fluoro-3-(1,1,2,3,3,3-hexafluoropropylthio)-2-methyl-1H-quinolin-4-one | 6-fluoro-3-(1,1,2,3,3,3-hexafluoropropylthio)-2-methyl-4-quinolone | MLS000077709 | SMR000042384 | cid_596487
Type:
Small organic molecule
Emp. Form.:
C13H8F7NOS
Mol. Mass.:
359.263
SMILES:
Cc1nc2ccc(F)cc2c(O)c1SC(F)(F)C(F)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: