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Target
Cathepsin S
Ligand
BDBM35503
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
13377.4±981.614 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM35503
Synonyms:
4-ethoxy-6-(1-piperidinyl)-1,3,5-triazine-2-carbonitrile | 4-ethoxy-6-piperidin-1-yl-1,3,5-triazine-2-carbonitrile | 4-ethoxy-6-piperidino-s-triazine-2-carbonitrile | MLS000043919 | SMR000021130 | cid_729558
Type:
Small organic molecule
Emp. Form.:
C11H15N5O
Mol. Mass.:
233.2697
SMILES:
CCOc1nc(nc(n1)N1CCCCC1)C#N
Structure:
Search PDB for entries with ligand similarity: