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Target
Cathepsin S
Ligand
BDBM41320
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41320
Synonyms:
4-(2,4-diketo-3-phenethyl-1H-quinazoline-7-carbonyl)piperazine-1-carboxylic acid ethyl ester | 4-[[2,4-dioxo-3-(2-phenylethyl)-1H-quinazolin-7-yl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester | MLS000086781 | SMR000022809 | cid_3239567 | ethyl 4-[2,4-dioxo-3-(2-phenylethyl)-1H-quinazoline-7-carbonyl]piperazine-1-carboxylate | ethyl 4-[[2,4-bis(oxidanylidene)-3-(2-phenylethyl)-1H-quinazolin-7-yl]carbonyl]piperazine-1-carboxylate | ethyl 4-{[2,4-dioxo-3-(2-phenylethyl)-1,2,3,4-tetrahydroquinazolin-7-yl]carbonyl}piperazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C24H26N4O5
Mol. Mass.:
450.487
SMILES:
CCOC(=O)N1CCN(CC1)C(=O)c1ccc2c(c1)[nH]c(=O)n(CCc1ccccc1)c2=O
Structure:
Search PDB for entries with ligand similarity: