Reaction Details Report a problem with these data
Target
Cathepsin S
Ligand
BDBM41372
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
11696±440.406 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41372
Synonyms:
1,5-dimethyl-N-(3-morpholin-4-ylpropyl)-4-oxidanylidene-pyrrolo[3,2-c]quinoline-2-carboxamide | 1,5-dimethyl-N-(3-morpholin-4-ylpropyl)-4-oxopyrrolo[3,2-c]quinoline-2-carboxamide | 1,5-dimethyl-N-[3-(4-morpholinyl)propyl]-4-oxo-2-pyrrolo[3,2-c]quinolinecarboxamide | 4-keto-1,5-dimethyl-N-(3-morpholinopropyl)pyrrolo[3,2-c]quinoline-2-carboxamide | MLS000118084 | SMR000095032 | cid_5309031
Type:
Small organic molecule
Emp. Form.:
C21H26N4O3
Mol. Mass.:
382.4561
SMILES:
Cn1c(cc2c1c1ccccc1n(C)c2=O)C(=O)NCCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity: