Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM32784
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
3255.8±1050.23 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM32784
Synonyms:
2-thiophenecarboxylic acid [5-amino-1-(benzenesulfonyl)-3-pyrazolyl] ester | 5-amino-1-(phenylsulfonyl)-1H-pyrazol-3-yl thiophene-2-carboxylate | CHEMBL389130 | MLS000044152 | SMR000021562 | [5-amino-1-(benzenesulfonyl)pyrazol-3-yl] thiophene-2-carboxylate | [5-azanyl-1-(phenylsulfonyl)pyrazol-3-yl] thiophene-2-carboxylate | cid_3243128 | thiophene-2-carboxylic acid (5-amino-1-besyl-pyrazol-3-yl) ester
Type:
Small organic molecule
Emp. Form.:
C14H11N3O4S2
Mol. Mass.:
349.385
SMILES:
Nc1cc(OC(=O)c2cccs2)nn1S(=O)(=O)c1ccccc1
Structure:
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