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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM30891
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Agonists of the S1P2 Receptor
EC50
3284±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Agonists of the S1P2 Receptor PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM30891
Synonyms:
MLS000049147 | N-(2-furanylmethyl)-7-hydroxy-2-oxo-1-benzopyran-3-carboxamide | N-(2-furfuryl)-7-hydroxy-2-keto-chromene-3-carboxamide | N-(2-furylmethyl)-7-hydroxy-2-oxo-2H-chromene-3-carboxamide | N-(furan-2-ylmethyl)-7-hydroxy-2-oxochromene-3-carboxamide | N-(furan-2-ylmethyl)-7-oxidanyl-2-oxidanylidene-chromene-3-carboxamide | SMR000074483 | cid_5398663
Type:
Small organic molecule
Emp. Form.:
C15H11NO5
Mol. Mass.:
285.2515
SMILES:
Oc1ccc2cc(C(=O)NCc3ccco3)c(=O)oc2c1
Structure:
Search PDB for entries with ligand similarity: