Reaction Details Report a problem with these data
Target
Bifunctional epoxide hydrolase 2
Ligand
BDBM41903
Substrate
n/a
Meas. Tech.
sEH_DR_Inh_Infinite200_Fluorescence_01072008
IC50
16.4±n/a nM
Citation
 PubChem, PC sEH_DR_Inh_Infinite200_Fluorescence_01072008 PubChem Bioassay (2008)[AID] 
Target
Name:
Bifunctional epoxide hydrolase 2
Synonyms:
Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic
Type:
Enzyme
Mol. Mass.:
62613.07
Organism:
Homo sapiens (Human)
Description:
P34913
Residue:
555
Sequence:
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM
  
Inhibitor
Name:
BDBM41903
Synonyms:
1-(2-pyrimidyl)-N-(4-sec-butylphenyl)nipecotamide | 1-Pyrimidin-2-yl-piperidine-3-carboxylic acid (4-sec-butyl-phenyl)-amide | MLS000033001 | N-(4-butan-2-ylphenyl)-1-(2-pyrimidinyl)-3-piperidinecarboxamide | N-(4-butan-2-ylphenyl)-1-pyrimidin-2-yl-piperidine-3-carboxamide | N-(4-butan-2-ylphenyl)-1-pyrimidin-2-ylpiperidine-3-carboxamide | SMR000006786 | cid_654683
Type:
Small organic molecule
Emp. Form.:
C20H26N4O
Mol. Mass.:
338.4466
SMILES:
CCC(C)c1ccc(NC(=O)C2CCCN(C2)c2ncccn2)cc1
Structure:
Search PDB for entries with ligand similarity: